Summaries by Inventor Van Dyke-Blodgett, Joshua

Biological and Biochemical Production of Enantiopure L-Piperazic Acid
Hu, Yifei ; Van Dyke-Blodgett, Joshua
T-017073

— Background: Compounds containing piperazic acid (Piz), a nonproteinogenic amino acid, are of significant interest for drug discovery. Peptidic compounds incorporating Piz as a building block include antibacterial, antiviral, immunomodulatory and anticancer drug leads, and all naturally-occurring Pi…

Biological and Biochemical Production of Enantiopure L-Piperazic Acid
Hu, Yifei ; Van Dyke-Blodgett, Joshua
T-017073

— Background: Compounds containing piperazic acid (Piz), a nonproteinogenic amino acid, are of significant interest for drug discovery. Peptidic compounds incorporating Piz as a building block include antibacterial, antiviral, immunomodulatory and anticancer drug leads, and all naturally-occurring Pi…

Clifednamide compounds
Qi, Yunci ; Van Dyke-Blodgett, Joshua ; Wencewicz, Timothy ; Yang, Jinping
T-019321

— Clifednamide A and C are congeners of long known ikarugamycin. Ikarugamycin has anti-inflammatory, anti-ciliate, plant modulatory and other desirable bioactivities. These clifednamide compounds may also have therapeutic, industrial or agricultural value. Publication: Qi, Y., Ding, E., & Blodget…

 

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